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PTCE Pharmacy Technician Certification (CPhT) Exam Questions and Answers

Questions 4

Which of the following medications is commercially available as an oral suspension that remains stable for a maximum of 10 days after reconstitution?

Options:

A.

Methylphenidate

B.

Famotidine

C.

Azithromycin

D.

Vancomycin

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Questions 5

Medications considered to have a narrow therapeutic index generally exhibit a(n):

Options:

A.

shorter window of guaranteed stability.

B.

incompatibility with therapeutic monitoring.

C.

synergistic effect on other medications.

D.

higher risk of causing serious toxicity.

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Questions 6

ReconstitutedArexvymust be discarded if it is not used within a maximum of:

Options:

A.

30 minutes

B.

4 hours

C.

24 hours

D.

1 week

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Questions 7

Which of the following medication pairs is an example of aLook-Alike, Sound-Alike (LASA) errorin which an antifungal drug is dispensed instead of an anesthetic drug?

Options:

A.

Diflucan and Diprivan

B.

Clonidine and Klonopin

C.

Metronidazole and Metformin

D.

Amiloride and Amlodipine

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Questions 8

According to federal law, the transfer of an eligible Schedule III controlled substance prescription must be communicated directly between:

Options:

A.

two licensed pharmacy technicians

B.

a licensed pharmacy technician and a licensed pharmacist

C.

a licensed pharmacist and a licensed nurse

D.

two licensed pharmacists

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Questions 9

Which of the following medication pairs is an example of aLook-Alike, Sound-Alike (LASA) errorin which an antifungal drug is dispensed instead of an anesthetic drug?

Options:

A.

Diflucan and Diprivan

B.

Clonidine and Klonopin

C.

Metronidazole and Metformin

D.

Amiloride and Amlodipine

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Questions 10

According tofederal law, records regarding thedistribution, receipt, or destructionofcontrolled substancesmust be maintained for a minimum ofhow many years?

Options:

A.

1

B.

2

C.

5

D.

7

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Questions 11

Which of the following products is acorticosteroid?

Options:

A.

Progesterone

B.

Fluocinolone

C.

Methyltestosterone

D.

Spironolactone

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Questions 12

Which of the following statements regardingspecific patient medication returns in the hospital settingis correct?

Options:

A.

Unlabeled medications may be dispensed by the nurse at discharge.

B.

Unopened units-of-use returned from outpatients may be redispensed.

C.

Unopened units-of-use returned from inpatients may be redispensed.

D.

Crediting of unused doses is not feasible.

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Questions 13

Which of the following medications is commercially available as both an oral tablet and an injection solution?

Options:

A.

Phenobarbital

B.

Paroxetine

C.

Pioglitazone

D.

Pramipexole

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Questions 14

Where permitted by state regulation, a pharmacy technician may be responsible for:

Options:

A.

Counseling patients on new prescriptions

B.

Completing a clinical review of new prescriptions

C.

Initiating the transfer of non-controlled substance prescriptions

D.

Approving the validity of controlled substance prescriptions

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Questions 15

Which of the following medications is an anticonvulsant used in the prophylaxis and control of various types of seizures?

Options:

A.

Clonidine

B.

Atomoxetine

C.

Guanfacine

D.

Phenytoin

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Questions 16

When dispensing cefdinir, the pharmacist should ascertain whether the patient is allergic to penicillin because:

Options:

A.

A penicillin allergy is a specific contraindication for this drug.

B.

Patients allergic to penicillin may also be allergic to fluoroquinolones.

C.

Patients allergic to penicillin may also be allergic to cephalosporins.

D.

A penicillin allergy indicates a high sensitivity to antibiotics.

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Questions 17

If 120 g of cream contains 3 g of drug, how many g of drug are in 2 oz of cream?

Options:

A.

1.5

B.

6

C.

15

D.

60

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Questions 18

According to the Institute for Safe Medication Practices (ISMP), which of the following is an example of a look-alike/sound-alike medication pair?

Options:

A.

Desipramine and desmopressin

B.

Chlordiazepoxide and chlorpromazine

C.

Fluoxetine and fluticasone

D.

Humalog and Humira

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Questions 19

A class III recall would be most appropriate to conduct for nystatin suspension that has been:

Options:

A.

Contaminated with bacteria.

B.

Found to contain carbamazepine.

C.

Contaminated with fungal spores.

D.

Labeled with an incorrect lot number.

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Questions 20

A prescription foracetaminophen 325 mg tabletswas inadvertently filled withacetaminophen 500 mg tablets, but the verifying pharmacist caught and corrected the mistake before dispensing. It would be most appropriate to report this situation as a(n):

Options:

A.

Near miss.

B.

Adverse drug reaction.

C.

Drug allergy.

D.

Sentinel event.

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Questions 21

Which of the following medication combinations should be avoided due to the increased potential forliver toxicity?

Options:

A.

Motrin and Ativan

B.

Motrin and Tylenol

C.

Percocet and Ativan

D.

Percocet and Tylenol

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Questions 22

Which of the following medications is subject to a Risk Evaluation and Mitigation Strategy (REMS) program because current patients should avoid becoming pregnant?

Options:

A.

Creon

B.

CellCept

C.

Celexa

D.

Cialis

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Questions 23

According to theDrug Enforcement Administration (DEA), prescriptions forcontrolled substancesmust include the:

Options:

A.

Patient’s diagnosis

B.

Date of issue

C.

Refill date

D.

Medication’s Schedule

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Questions 24

Which of the following medications is indicated to treat mild, moderate, or severe dementia of the Alzheimer type?

Options:

A.

Aricept

B.

Azilect

C.

Ambien

D.

Atacand

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Questions 25

A prescriber orders1000 mgof a medication. If the stock bottle label stateseach tablet contains 0.1 g, how many tablets should the patient receive?

Options:

A.

1

B.

10

C.

100

D.

1000

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Questions 26

While compounding anonsterile preparation, physical incompatibilities may be avoided by following the specific mixing instructions found in the:

Options:

A.

Medication Guide

B.

Master Formulation Record

C.

Patient Package Insert

D.

Safety Data Sheet (SDS)

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Questions 27

The master formulation record is used to help:

Options:

A.

ensure quality control.

B.

prevent drug diversion.

C.

eliminate patient profiles.

D.

guarantee drug availability.

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Questions 28

Which of the following questions from a nurse must be referred to a pharmacist?

Options:

A.

"What is the generic name for the antibiotic the prescriber wrote?"

B.

"What is the schedule for my patient's IV antibiotic?"

C.

"Can I piggyback my patient’s IV antibiotic with her heparin drip?"

D.

"Does the IV antibiotic require prior authorization from my patient's insurance?"

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Questions 29

When used on a prescription, "SL" refers to a specific:

Options:

A.

Package size

B.

Route of administration

C.

Medication strength

D.

Disease state

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Questions 30

Retin-A should be stored with the:

Options:

A.

Liquid preparations.

B.

Chemotherapy drugs.

C.

Refrigerated drugs.

D.

Topical preparations.

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Questions 31

Conducting a root-cause analysis (RCA) helps pharmacy staff to:

Options:

A.

determine which medication should be dispensed.

B.

decipher prescriber handwriting during order entry.

C.

increase pharmacy revenue and inventory turnover.

D.

identify the factors that contributed to a problem or event.

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Questions 32

Themiddle series of numbersin theNational Drug Code (NDC)is used for:

Options:

A.

Identification of therapeutic class

B.

Locating expired medication on the shelf

C.

Proper storage of the medication

D.

Accurate product selection

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Questions 33

According tofederal law, aSchedule III narcotic drug prescriptionmay be filled a maximum of how many times?

Options:

A.

3

B.

4

C.

6

D.

12

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Questions 34

Behind-the-counter decongestant products containingpseudoephedrinemust be used with caution in patients with:

Options:

A.

Asthma

B.

Hypertension

C.

Hypokalemia

D.

Eczema

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Questions 35

A prescription reads:

Famotidine 40 mg/5 mL

Quantity: 50 mL

Sig: 0.4 mL PO t.i.d.

What amount of medication, in mg, is given each day?

Options:

A.

1.2 mg

B.

3.2 mg

C.

6.4 mg

D.

9.6 mg

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Questions 36

What type ofmedication erroris described asa mistake in prescribing, dispensing, or planned medication administration that is detected and corrected before reaching the patient?

Options:

A.

Compliance error

B.

Monitoring error

C.

Omission error

D.

Potential error

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Questions 37

Which of the following is a common side effect of amlodipine?

Options:

A.

Dizziness

B.

Photosensitivity

C.

Agitation

D.

Insomnia

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Questions 38

Aspacerwas prescribed to accompany ametered dose inhaler (MDI), but the patient never picked it up. The spacer should be returned to:

Options:

A.

Damaged stock

B.

The manufacturer

C.

The study sponsor

D.

Dispensing stock

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Questions 39

Medications considered to have anarrow therapeutic index (NTI)generally exhibita(n):

Options:

A.

Shorter window of guaranteed stability.

B.

Incompatibility with therapeutic monitoring.

C.

Synergistic effect on other medications.

D.

Higher risk of causing serious toxicity.

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Questions 40

A prescription calls for one capsule of a medication to be administered PO ac. daily for 14 days. What directions should appear on the label?

Options:

A.

Take one capsule by mouth daily for 14 days.

B.

Take one capsule by mouth after a meal once daily for 14 days.

C.

Take one capsule by mouth before a meal once daily for 14 days.

D.

Take one capsule by mouth with a meal once daily for 14 days.

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Questions 41

A hospital pharmacy implemented a voluntary medication error reporting system to improve patient safety. Two months later, the medication error rate had increased by 33%. Which of the following is most likely to be the reason for this increase?

Options:

A.

Culture change resulted in increased error reporting

B.

Culture change resulted in a punitive environment

C.

Focus on errors led to decreased focus on dispensing

D.

Focus on compliance with culture stimulated false reporting

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Questions 42

Which of the following isleast likelyto causesignificant patient harmif used in error?

Options:

A.

Topical creams

B.

Injectable insulins

C.

Antineoplastic agents

D.

Oral anticoagulants

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Questions 43

Which of the following medications is available only with a prescription?

Options:

A.

Pantoprazole

B.

Omeprazole

C.

Lansoprazole

D.

Esomeprazole

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Questions 44

The label of a stock bottle provides the following information:

(01)55555444422

(1)051526

(10)ABC123

(21)11262026

What is the lot number for this medication?

Options:

A.

ABC123

B.

55555444422

C.

051526

D.

11262026

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Questions 45

The transport of a hazardous waste container to a storage site must be done by individuals who meet the mandated hazardous waste training given by which organization?

Options:

A.

DEA

B.

FDA

C.

OSHA

D.

ISMP

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Questions 46

An error that has the potential to cause harm but is caught and corrected before it reaches the patient should be reported as a(n):

Options:

A.

Adverse drug event (ADE)

B.

Recall

C.

Near miss

D.

Root-cause analysis (RCA)

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Questions 47

A patient package insert (PPI) is required for which of the following medications?

Options:

A.

Androgens

B.

Oral contraceptives

C.

Corticosteroids

D.

Oral chemotherapy

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Questions 48

According to the manufacturer, Risperdal Consta remains stable at room temperature for a maximum of:

Options:

A.

12 hours

B.

7 days

C.

14 days

D.

21 days

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Questions 49

Cyanocobalamin is indicated to treat:

Options:

A.

pernicious anemia

B.

alcohol withdrawal

C.

hypothyroidism

D.

narrow-angle glaucoma

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Questions 50

Counting trays should be cleaned frequently to:

Options:

A.

Eliminate decontamination

B.

Remove residue

C.

Guarantee aseptic technique

D.

Promote allergic reactions

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Questions 51

How many2 oz bottlescan be filled if100 mL of a 20% solutionis diluted to make a2% solution?

Options:

A.

10

B.

16

C.

27

D.

33

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Questions 52

According to federal law, a prescription for a Schedule IV controlled substance may be refilled a maximum of:

Options:

A.

2 times in 3 months.

B.

3 times in 4 months.

C.

4 times in 6 months.

D.

5 times in 6 months.

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Questions 53

An outsourcing facility mislabeled enoxaparin syringes asphytonadione syringesand sent them out to multiple facilities. Which type of recall would be most appropriate to issue?

Options:

A.

Class I

B.

Class II

C.

Class III

D.

Misbranding

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Questions 54

According to the FDA, a Medication Guide must be given to the patient when dispensing:

Options:

A.

zafirlukast.

B.

Zestril.

C.

zinc.

D.

Zyprexa.

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Questions 55

Which of the following suppositories should be shipped to the pharmacy in arefrigerated container?

Options:

A.

Promethazine

B.

Prochlorperazine

C.

Hydrocortisone

D.

Bisacodyl

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Questions 56

Which of the following is an event that must be reported to VAERS if it occurs after vaccine administration?

Options:

A.

Constipation

B.

Anaphylaxis

C.

Drowsiness

D.

Hyperlipidemia

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Questions 57

The label of a stock bottle provides the following information:

(01)55555444422

(1)051526

(10)ABC123

(21)11262026

What is the lot number for this medication?

Options:

A.

ABC123

B.

55555444422

C.

051526

D.

11262026

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Questions 58

A physician writes the prescription "Lactulose syrup 1 tbsp PO t.i.d." What volume, in mL, should the patient take daily?

Options:

A.

15

B.

30

C.

45

D.

60

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Questions 59

What volume, inmL, of morphine sulfate that comes in10 mL vials at a concentration of 5 mg/mLwill be needed to fill an order for25 mg?

Options:

A.

0.5

B.

2

C.

2.5

D.

5

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Questions 60

Which of the following is an OTC medication indicated to treat motion sickness?

Options:

A.

Meclizine

B.

Olanzapine

C.

Promethazine

D.

Scopolamine

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Questions 61

In order to maintain proper storage conditions, which of the following medications must be dispensed in its original container?

Options:

A.

Methotrexate

B.

Metoprolol XL

C.

Nitroglycerin SL

D.

Allopurinol

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Questions 62

Which of the following auxiliary labels would be most appropriate to affix to a bottle ofcephalexin oral suspensionafter reconstitution?

Options:

A.

Protect from light; Discard after 7 days

B.

Protect from light; Discard after 14 days

C.

Keep refrigerated; Discard after 7 days

D.

Keep refrigerated; Discard after 14 days

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Questions 63

Carvedilolmay be a suitable therapeutic substitution for:

Options:

A.

Albuterol

B.

Labetalol

C.

Tramadol

D.

Estradiol

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Questions 64

Bottles of hydralazine and hydroxyzine are located next to each other on the same shelf in the pharmacy. Before counting the medication, a helpful patient safety procedure would be to verify the:

Options:

A.

Dosage strength

B.

Color of the tablet

C.

NDC number

D.

Lot number

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Questions 65

Therapeutic equivalence (TE) codesmay be found in:

Options:

A.

Remington: The Science and Practice of Pharmacy.

B.

The Orange Book.

C.

Safety Data Sheets (SDSs).

D.

The package insert.

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Questions 66

A patient fills a prescription for a 30-day supply of amlodipine 10 mg. Two days later, the patient brings in a prescription for diltiazem 30 mg from their primary careprovider. Which of the following rejection messages is the pharmacy technician most likely to receive?

Options:

A.

Prior authorization required

B.

Therapeutic duplication

C.

NDC not covered

D.

Refill too soon

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Questions 67

The adult dose of a medication is 10 mg/kg of body weight. What dose, in g, should be given to a patient weighing 220 lb?

Options:

A.

1

B.

10

C.

100

D.

1000

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Questions 68

What volume (in mL) of adexamethasone injection (20 mg/mL)is required to administer a30 mg dose?

Options:

A.

0.15

B.

0.67

C.

1.5

D.

6.7

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Questions 69

Which of the following medications would require the auxiliary label"Do not lie down for 30 minutes after taking"?

Options:

A.

Risedronate

B.

Ropinirole

C.

Repaglinide

D.

Rifampin

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Questions 70

According to the Institute for Safe Medication Practices (ISMP), which of the following is a high-alert medication in an acute care setting?

Options:

A.

Normal saline solution

B.

Transdermal lidocaine

C.

Dextrose 5% solution

D.

Insulin U-500

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Questions 71

Which of the following auxiliary labels would be most appropriate to affix to a bottle ofcephalexin oral suspensionafter reconstitution?

Options:

A.

Protect from light; Discard after 7 days

B.

Protect from light; Discard after 14 days

C.

Keep refrigerated; Discard after 7 days

D.

Keep refrigerated; Discard after 14 days

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Questions 72

The pharmacy must have the results of a currentANC (Absolute Neutrophil Count) and WBC (White Blood Cell) blood testprior to dispensing which medication?

Options:

A.

Aripiprazole

B.

Fluoxetine

C.

Amitriptyline

D.

Clozapine

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Questions 73

A prescription reads:

Famotidine 40 mg/5 mL

Quantity: 50 mL

Sig: 0.4 mL PO t.i.d.

What amount of medication, in mg, is given each day?

Options:

A.

1.2 mg

B.

3.2 mg

C.

6.4 mg

D.

9.6 mg

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Questions 74

Eliquis is considered ahigh-alert medicationbecause it can cause potentially fatal:

Options:

A.

Respiratory depression

B.

Bleeding

C.

Hyperglycemia

D.

Hypoxia

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Questions 75

Adsorptionis most likely to cause a medication to:

Options:

A.

Lose potency.

B.

Become contaminated.

C.

Require refrigeration.

D.

Trigger anaphylaxis.

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Questions 76

Which of the following should be taken on anempty stomach?

Options:

A.

Levothyroxine

B.

Amlodipine

C.

Cyclobenzaprine

D.

Loratadine

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Questions 77

Desvenlafaxineis indicated to treat:

Options:

A.

Hypertension

B.

Major depressive disorder

C.

Benign prostatic hypertrophy

D.

Atrial fibrillation

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Questions 78

Which of the followingmedications should be pulled from inventorydue to incorrect storage?

Options:

A.

Boostrix that was stored in a refrigerator.

B.

Havrix that was stored in a refrigerator.

C.

Shingrix that was stored in a freezer.

D.

Varivax that was stored in a freezer.

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Questions 79

A physician prescribes5 mg/kgof a drugtwice dailyfor a patient weighing110 lbs. How many0.5 g tabletsof the drug are required for a10-day duration?

Options:

A.

5

B.

10

C.

20

D.

40

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Questions 80

Vistarilis a brand name for:

Options:

A.

Prochlorperazine

B.

Meclizine

C.

Ranolazine

D.

Hydroxyzine

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Questions 81

Which of the following is most likely to be used as a substitute if the non-formulary drug is escitalopram?

Options:

A.

Cabergoline

B.

Ciprofloxacin

C.

Sertraline

D.

Amantadine

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Questions 82

If a medication's expiration date lists only the month and year, the intended expiration date is the:

Options:

A.

First day of the month

B.

Tenth day of the month

C.

Fifteenth day of the month

D.

Last day of the month

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Questions 83

The generic name for which of the following medications is paired with oxaprozin on the list of confused drug names?

Options:

A.

Tobradex

B.

Topamax

C.

Tradjenta

D.

Trileptal

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Questions 84

According to theFDA,heparin strength per total volumeshould be the primary and prominent expression on the manufacturer’s label, followed by the:

Options:

A.

Percentage weight per volume

B.

Volume per total strength

C.

Strength per mL enclosed in parentheses

D.

mL per dose enclosed in parentheses

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Questions 85

What is the generic name for Lipitor?

Options:

A.

Provastatin

B.

Fluvastatin

C.

Simvastatin

D.

Atorvastatin

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Questions 86

According to federal law, the receiving pharmacy must note which of the following on a transferred controlled substance prescription?

Options:

A.

The date of the original dispensing

B.

The medication's expiration date

C.

The prescriber's DEA number

D.

The receiving pharmacy's DEA number

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Questions 87

A package with the NDC: 76439-103-10 contains the same medication as a package with which of the following NDCs?

Options:

A.

76439-208-10

B.

76439-103-50

C.

74693-103-10

D.

74693-206-50

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Questions 88

If M-M-R II antigen were inadvertently reconstituted with a stock vial of normal saline, pharmacy staff should:

Options:

A.

administer the vaccine as the diluents are equivalent.

B.

report the incident to the Drug Enforcement Administration (DEA).

C.

contact the Environmental Protection Agency (EPA) for guidance.

D.

discard the vaccine as its efficacy could be altered.

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Questions 89

Prior to dispensing, the recommended storage temperature for NuvaRing is:

Options:

A.

Freezer, at -20°C to -10°C (-4°F to 14°F).

B.

Refrigerator, at 2°C to 8°C (36°F to 46°F).

C.

Cool, at 8°C to 15°C (46°F to 59°F).

D.

Room temperature, at 15°C to 30°C (59°F to 86°F).

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Questions 90

Pristiq has the same mechanism of action as:

Options:

A.

valacyclovir

B.

varenicline

C.

venlafaxine

D.

verapamil

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Questions 91

According to the Institute for Safe Medication Practices (ISMP), which of the following is a high-alert medication in an acute care setting?

Options:

A.

Normal saline solution

B.

Transdermal lidocaine

C.

Dextrose 5% solution

D.

Insulin U-500

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Questions 92

During final verification, a pharmacist identifies that a prescription written for ampicillin was entered as amoxicillin. The pharmacist corrects the error and the patient receives the prescribed ampicillin. This situation may be reported as a(n):

Options:

A.

near miss

B.

dispensing error

C.

adverse event

D.

unauthorized drug

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Questions 93

Which of the following is a controlled substance?

Options:

A.

Metoprolol

B.

Butorphanol

C.

Carvedilol

D.

Propranolol

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Exam Code: PTCE
Exam Name: Pharmacy Technician Certification (CPhT) Exam
Last Update: Nov 21, 2025
Questions: 313

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